Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199231 | 0.81 | ALDH1A1 (0.47) | DAOKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL10487074 | 0.74 | DAO (0.51) | DAOHCAR2PDE3BPDE3AIDH1 | |
| SCHEMBL856053 | 0.73 | POLB (0.56) | DAOHCAR2PDE3BPDE3AIDH1 | |
| SCHEMBL5184666 | 0.73 | PDE10A (0.43) | DAOPDE3BPDE3A | |
| SCHEMBL441514 | 0.73 | SLC2A1 (0.43) | DAOPDE3BPDE3AIDH1KDM4E | |
| SCHEMBL14719553 | 0.70 | HCAR2 (0.56) | DAOHCAR2PDE3BPDE3AIDH1 | |
| SCHEMBL30107633 | 0.70 | HCAR2 (0.56) | DAOHCAR2PDE3BPDE3AIDH1 | |
| SCHEMBL3300303 | 0.69 | TAAR1 (0.60) | DAOHCAR2IDH1ALDH1A1CYP3A4 | |
| SCHEMBL14485841 | 0.69 | DAO (1.00) | DAO | |
| SCHEMBL6647299 | 0.68 | DAO (0.52) | DAOHCAR2PDE3BPDE3AIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |