Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139312 | 0.84 | CYP1A2 (0.64) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 | |
| SCHEMBL18002532 | 0.82 | P2RX4 (0.45) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 | |
| SCHEMBL16406720 | 0.82 | P2RX4 (0.45) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 | |
| SCHEMBL21944815 | 0.82 | P2RX4 (0.45) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 | |
| SCHEMBL1133138 | 0.81 | ALDH1A1 (0.53) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 | |
| SCHEMBL8991562 | 0.80 | ALDH1A1 (0.50) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 | |
| SCHEMBL11991407 | 0.80 | PSEN1 (0.47) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 | |
| SCHEMBL14297598 | 0.80 | PSEN1 (0.47) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 | |
| SCHEMBL802905 | 0.80 | PSEN1 (0.47) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 | |
| SCHEMBL18932202 | 0.80 | PSEN1 (0.47) | CYP1A2CYP2D6CYP2C9XBP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864217-B2 | Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice | HOECHST SCHERING AGREVO GMBH (DE) | 2005-03-08 | — | — | US | claimed |
| US-20030191025-A1 | Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-10-09 | — | — | US | claimed |
| US-8580992-B1 | Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis | The Florida State University Research Foundation, Inc. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8334414-B2 | Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2012-12-18 | — | — | US | disclosed |
| CN-101390852-B | Melanogenesis inhibitor and skin preparation containing the same | TAKASAGO PERFUMERY CO LTD | 2010-12-08 | — | — | CN | disclosed |
| US-7754909-B1 | Compounds and methods of arylmethylation (benzylation) as protection for alcohol groups during chemical synthesis | The Florida State University Research Foundation, Inc. (US) | 2010-07-13 | — | — | US | disclosed |
| CN-1747711-B | Melanogenesis inhibitor and skin preparation containing the same | TAKASAGO PERFUMERY CO LTD | 2010-04-28 | — | — | CN | disclosed |
| CN-101390852-A | Melanogenesis inhibitor and skin preparation containing the same | TAKASAGO PERFUMERY CO LTD (JP) | 2009-03-25 | — | — | CN | disclosed |
| CN-1747711-A | Melanogenesis inhibitor and skin preparation containing the same | TAKASAGO PERFUMERY CO LTD (JP) | 2006-03-15 | — | — | CN | disclosed |
| US-6864217-B2 | Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice | HOECHST SCHERING AGREVO GMBH (DE) | 2005-03-08 | — | — | US | disclosed |
| US-20030191025-A1 | Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-10-09 | — | — | US | disclosed |
| US-6492301-B1 | SYNERGISTIC WITH HERBICIDES WHICH ARE SELECTIVE IN RICE, MAINLY AGAINST GRASSES, DICOTYLEDONS AND CYPERACEAE PLANTS | HOECHST SCHERING AGREVO GMBH (DE) | 2002-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191025-A1 | Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice | DDT, CYCS, CBR3 | CYP1A2 75/4885CYP2D6 106/4885CYP2C9 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.