SCHEMBL6473228

SCHEMBL6473228

CC(C)(C)c1cccc(-c2ccc(-c3ccc(-c4ccc(-c5ccc(-c6cc(C(C)(C)C)cc(C(C)(C)C)c6)cc5)cc4)cc3)cc2C(C)(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.51
RXRB P28702 8/20 0.50
RXRA P19793 7/20 0.50
RXRG P48443 3/20 0.42
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
CNR1 P21554 1/20 0.38
PTPN5 P54829 1/20 0.38
DHODH Q02127 1/20 0.37
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
NPC1 O15118 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
SENP8 Q96LD8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3693634 1.00 KIF11 (0.51) KIF11RXRBRXRARXRGALDH1A1
SCHEMBL4316640 0.90 RXRB (0.46) KIF11RXRBRXRARXRGMAPT
SCHEMBL29373306 0.82 KIF11 (0.64) KIF11RXRBRXRARXRGMAPT
SCHEMBL27908559 0.80 KIF11 (0.46) KIF11RXRBRXRAALDH1A1MAPT
SCHEMBL27659191 0.78 KIF11 (0.76) KIF11RXRBRXRARXRGALDH1A1
SCHEMBL25522328 0.77 RXRB (0.56) KIF11RXRBRXRARXRGALDH1A1
SCHEMBL668815 0.77 MEN1 (0.42) KIF11RXRBRXRAALDH1A1MAPT
SCHEMBL17105790 0.77 KIF11 (0.68) KIF11RXRBRXRAALDH1A1MAPT
SCHEMBL25911308 0.76 RXRB (0.63) KIF11RXRBRXRARXRGMAPT
SCHEMBL25706667 0.76 KIF11 (0.67) KIF11RXRBRXRARXRGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050110978-A1 Method of authenticating articles, authenticatable polymers, and authenticatable articles SABIC INNOVATIVE PLASTICS IP B.V. 2005-05-26 US disclosed