SCHEMBL4316640

SCHEMBL4316640

CC(C)(C)c1cc(-c2ccc(-c3ccc(-c4ccc(-c5ccc(-c6ccccc6)c(C(C)(C)C)c5)c(C(C)(C)C)c4)cc3)cc2)cc(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRB P28702 8/20 0.46
RXRA P19793 7/20 0.46
RXRG P48443 3/20 0.46
KIF11 P52732 1/20 0.40
DHODH Q02127 1/20 0.37
EGFR P00533 1/20 0.36
TRPA1 O75762 1/20 0.35
CNR1 P21554 1/20 0.35
PTPN5 P54829 1/20 0.35
MEN1 O00255 1/20 0.35
APAF1 O14727 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
XBP1 P17861 1/20 0.35
PTBP1 P26599 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
GALK1 P51570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6473228 0.90 KIF11 (0.51) RXRBRXRARXRGKIF11DHODH
SCHEMBL3693634 0.90 KIF11 (0.51) RXRBRXRARXRGKIF11DHODH
SCHEMBL668815 0.88 MEN1 (0.42) RXRBRXRAKIF11EGFRTRPA1
SCHEMBL7067289 0.83 NPC1 (0.46) RXRBRXRAKIF11DHODHCNR1
SCHEMBL30524348 0.83 NPC1 (0.46) RXRBRXRAKIF11DHODHCNR1
SCHEMBL27757672 0.82 RXRB (0.62) RXRBRXRARXRGKIF11DHODH
SCHEMBL1532680 0.81 RXRB (0.50) RXRBRXRARXRGKIF11DHODH
SCHEMBL4309659 0.81 RXRB (0.50) RXRBRXRARXRGKIF11DHODH
SCHEMBL1537452 0.81 RXRB (0.50) RXRBRXRARXRGKIF11DHODH
SCHEMBL76093 0.81 RXRB (0.50) RXRBRXRARXRGKIF11DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7508499-B2 Methods for application of a tag onto a media article GENERAL ELECTRIC COMPANY (US) 2009-03-24 US disclosed
EP-1573728-B1 METHODS FOR APPLICATION OF TAGS ONTO OPTICAL MEDIA ARTICLES GEN ELECTRIC (US) 2007-04-04 EP disclosed
EP-1573728-A1 METHODS FOR APPLICATION OF TAGS ONTO OPTICAL MEDIA ARTICLES GENERAL ELECTRIC COMPANY (US) 2005-09-14 EP disclosed
US-20050167510-A1 Methods for application of a tag onto a media article GENERAL ELECTRIC COMPANY 2005-08-04 US disclosed
WO-2004055802-A1 METHODS FOR APPLICATION OF TAGS ONTO OPTICAL MEDIA ARTICLES GENERAL ELECTRIC COMPANY (US) 2004-07-01 WO disclosed
US-20040115421-A1 Methods for application of tags onto optical media articles GENERAL ELECTRIC COMPANY 2004-06-17 US disclosed