Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998298 | 0.81 | KDM1A (0.57) | MAOBMAOAKDM1A | |
| SCHEMBL15778838 | 0.80 | KDM1A (0.69) | OPRM1OPRL1MAPTALDH1A1HPGD | |
| SCHEMBL28244237 | 0.77 | OPRM1 (0.45) | OPRM1OPRL1MAPTALDH1A1HPGD | |
| SCHEMBL17591832 | 0.74 | ACP3 (0.43) | OPRM1OPRL1MAPTALDH1A1HPGD | |
| SCHEMBL6317162 | 0.74 | MAPT (0.42) | OPRM1OPRL1MAPTALDH1A1HPGD | |
| SCHEMBL13888944 | 0.74 | MAOB (0.50) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12188964 | 0.74 | MAOB (0.50) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6320891 | 0.73 | ITGB3 (0.51) | OPRM1OPRL1MAPTALDH1A1HPGD | |
| SCHEMBL1975325 | 0.73 | PLK4 (0.55) | ALDH1A1KDM4E | |
| SCHEMBL1973991 | 0.73 | PLK4 (0.55) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007659-A2 | DIKETIMINATO CU(I) AND CO(I) CARBENE CATALYSTS, AND CYCLOPROPANATION METHODS USING THEM | GEORGETOWN UNIVERSITY (US) | 2005-01-27 | — | — | WO | disclosed |