Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CLPP | Q16740 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473831 | 0.81 | VNN1 (0.43) | VNN1MAPK14GRIN1GRIN2BKDM4E | |
| SCHEMBL6471834 | 0.74 | NTRK1 (0.38) | VNN1MAPK14BRD4 | |
| SCHEMBL25782971 | 0.73 | NTRK1 (0.40) | MAPK14IDH1 | |
| SCHEMBL4387481 | 0.72 | MAPK14 (0.59) | VNN1MAPK14GRIN1GRIN2BKDM4E | |
| SCHEMBL29594334 | 0.72 | MAPK14 (0.59) | VNN1MAPK14GRIN1GRIN2BKDM4E | |
| SCHEMBL6471709 | 0.72 | MAPK14 (0.56) | MAPK14KDM4EPARP1PARP3 | |
| SCHEMBL4379238 | 0.70 | MAPK14 (0.57) | VNN1MAPK14GRIN1GRIN2BKDM4E | |
| SCHEMBL6471265 | 0.70 | MAPK14 (0.40) | VNN1MAPK14KDM4EIDH1 | |
| SCHEMBL3522226 | 0.67 | MAPK14 (0.51) | VNN1MAPK14GRIN1GRIN2BKDM4E | |
| SCHEMBL4380849 | 0.64 | MAPK14 (0.58) | VNN1MAPK14KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |