Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | CASP6 | P55212 | 3/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11506068 | 0.82 | HPGD (0.38) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL949237 | 0.79 | HPGD (0.50) | KMT2AHPGDNOTUMCASP3CASP6 | |
| SCHEMBL10482902 | 0.78 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL10482901 | 0.78 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL6649905 | 0.74 | ALDH1A1 (0.45) | KMT2AALDH1A1MEN1MAPTCYP3A4 | |
| SCHEMBL7829086 | 0.74 | ALDH1A1 (0.57) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL21311764 | 0.74 | KMT2A (0.57) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL16835531 | 0.71 | HPGD (0.64) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL13727309 | 0.70 | POLB (0.47) | ALDH1A1MAPTHPGDNOTUMCYP2A6 | |
| SCHEMBL24119281 | 0.70 | KMT2A (0.53) | KMT2AALDH1A1MEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4559174-A | NITRATION, REDUCTION AND HYDROLYSIS OF 5-CYANO5H-DIBENZ/B,FLAZEPINE | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | claimed |
| EP-0028028-B1 | PROCESSES FOR THE PREPARATION OF AN OXO COMPOUND, AND INTERMEDIATES REQUIRED THEREFOR | CIBA-GEIGY AG (CH) | 1985-05-22 | — | — | EP | claimed |
| EP-0028028-A2 | Processes for the preparation of an oxo compound, and intermediates required therefor | CIBA-GEIGY AG (CH) | 1981-05-06 | — | — | EP | claimed |
| JP-1045367-A | — | — | None | — | — | JP | disclosed |
| CN-120698931-A | Preparation method of oxcarbazepine | 河北科技大学 | 2025-09-26 | — | — | CN | disclosed |
| EP-2697662-B1 | BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF | CODEXIS INC (US) | 2018-06-06 | — | — | EP | disclosed |
| US-9963683-B2 | Biocatalytic process for preparing eslicarbazepine and analogs thereof | CODEXIS, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| US-9963683-B2 | Biocatalytic process for preparing eslicarbazepine and analogs thereof | CODEXIS, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| US-20170159028-A1 | BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-06-08 | — | — | US | disclosed |
| US-20170159028-A1 | BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2017-06-08 | — | — | US | disclosed |
| US-9605290-B2 | Biocatalytic process for preparing eslicarbazepine and analogs thereof | CODEXIS, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-6384217-B1 | INTERMEDIATES FOR PRODUCTION OF CARBAMAZEPINE AND OXCARBAMAZEPINE | FARCHEMIA S.R.L. (IT) | 2002-05-07 | — | — | US | disclosed |
| WO-2002006284-A1 | INDOLOQUINAZOLINONES | NOVARTIS AG (CH) | 2002-01-24 | — | — | WO | disclosed |
| EP-1127877-A2 | 5-Cyano-10-hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine, processes for its preparation and for its conversion into 5-carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine or into 5-carbamoyl-5H-dibenz[b,f]azepine | FARCHEMIA S.r.l. (IT) | 2001-08-29 | — | — | EP | disclosed |
| US-4579683-A | 5-Cyano-10-isonitroso-10,11-dihydro-5H-dibenz[b,f]azepine | CIBA-GEIGY CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |
| US-4559174-A | NITRATION, REDUCTION AND HYDROLYSIS OF 5-CYANO5H-DIBENZ/B,FLAZEPINE | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| US-4540514-A | 5-Cyano- and 5-carbamoyl-10-nitro-5H-dibenz[b,f]azepine | CIBA-GEIGY CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0028028-B1 | PROCESSES FOR THE PREPARATION OF AN OXO COMPOUND, AND INTERMEDIATES REQUIRED THEREFOR | CIBA-GEIGY AG (CH) | 1985-05-22 | — | — | EP | disclosed |
| US-4452738-A | Process for the manufacture of 5-carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,]azepine | CIBA-GEIGY CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0028028-A2 | Processes for the preparation of an oxo compound, and intermediates required therefor | CIBA-GEIGY AG (CH) | 1981-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170159028-A1 | BIOCATALYTIC PROCESS FOR PREPARING ESLICARBAZEPINE AND ANALOGS THEREOF | BACE1, BACE2, GSAP | KMT2A 306/4885ALDH1A1 281/4885MEN1 3740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.