Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115243 | 0.93 | HTT (0.59) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL5077234 | 0.93 | HTT (0.59) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL14313090 | 0.93 | HTT (0.59) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL895978 | 0.93 | HTT (0.77) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL5141182 | 0.91 | HTT (0.60) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL26962003 | 0.86 | SMN1; SMN2 (0.67) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL26962235 | 0.86 | SMN1; SMN2 (0.67) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL16025051 | 0.84 | SMN1; SMN2 (0.68) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL631512 | 0.84 | SMN1; SMN2 (0.68) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL14348062 | 0.84 | SMN1; SMN2 (0.68) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-06-02 | — | — | US | disclosed |
| US-20050107423-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-19 | — | — | US | disclosed |
| WO-2005026165-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |
| EP-1401830-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | WARNER-LAMBERT COMPANY | 2003-06-19 | — | — | US | disclosed |
| WO-2002102793-A2 | QUINAZOLINEDIONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114666-A1 | Having quinazolindione core structure; non-antibiotic resistance | ABCC1, RPS6KA1, SIGMAR1 | HTT 4546/4885SMN1; SMN2 4744/4885NPC1 418/4885 |
| US-20050119231-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | HTT 4661/4885SMN1; SMN2 3447/4885NPC1 1057/4885 |
| US-20050107423-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | HTT 4661/4885SMN1; SMN2 3447/4885NPC1 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.