Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412379 | 0.83 | CHRM1 (0.54) | ALDH1A1HDAC4HDAC2HDAC8LMNA | |
| SCHEMBL3721172 | 0.83 | CHRM1 (0.54) | ALDH1A1HDAC4HDAC2HDAC8LMNA | |
| SCHEMBL6473873 | 0.82 | HSP90AA1 (0.41) | ALDH1A1HDAC4HDAC2HDAC8LMNA | |
| SCHEMBL11296361 | 0.82 | TBXAS1 (0.34) | ALDH1A1MAPTNPSR1HTTTRIM24 | |
| SCHEMBL2167352 | 0.81 | CHRM3 (0.38) | ALDH1A1HDAC4HDAC2HDAC8LMNA | |
| SCHEMBL7752284 | 0.81 | CHRM3 (0.38) | ALDH1A1HDAC4HDAC2HDAC8LMNA | |
| SCHEMBL722593 | 0.81 | CHRM3 (0.38) | ALDH1A1HDAC4HDAC2HDAC8LMNA | |
| SCHEMBL19212491 | 0.79 | ALDH1A1 (0.35) | ALDH1A1LMNAKDM4EGAASMN1; SMN2 | |
| SCHEMBL4189998 | 0.79 | MAPT (0.38) | ALDH1A1HDAC4HDAC2HDAC8LMNA | |
| SCHEMBL10106396 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HDAC4HDAC2HDAC8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364966-A1 | Process for preparation of 3-(2-hydroxy-5-substituted phenyl)-3-phenylpropylamines, intermediates for making hydroxytolterodine | LEK Pharmaceuticals d.d. (SI) | 2011-09-14 | — | — | EP | disclosed |