Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 9/20 | 0.43 |
| ▸ | HTR7 | P34969 | 9/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5617249 | 0.99 | KCNH2 (0.46) | KCNH2DRD2DRD3DRD4DRD5 | |
| Hydrochloric Acid SCHEMBL5617307 | 0.97 | CYP2D6 (0.43) | KCNH2DRD2DRD3DRD4DRD5 | |
| SCHEMBL6473544 | 0.87 | DRD2 (0.48) | DRD2DRD3HTR1AHTR7HTR2A | |
| Hydrochloric Acid SCHEMBL5655044 | 0.86 | DRD2 (0.48) | DRD2DRD3HTR1AHTR7HTR2A | |
| SCHEMBL6483259 | 0.85 | HTR1A (0.51) | DRD2DRD3DRD5HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL5617457 | 0.84 | HTR1A (0.51) | DRD2DRD3DRD5HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL5617301 | 0.80 | HRH3 (0.34) | SIGMAR1HRH1 | |
| SCHEMBL7850061 | 0.76 | KCNH2 (0.51) | KCNH2DRD2DRD3CYP2D6HTR1A | |
| Hydrochloric Acid SCHEMBL5617435 | 0.75 | DRD2 (0.47) | DRD2DRD3DRD5HTR1AHTR7 | |
| SCHEMBL14383290 | 0.74 | CHRM1 (0.55) | KCNH2DRD2DRD3CYP2D6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960579-B1 | Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders | ALCON MANUFACTURING, LTD. (US) | 2005-11-01 | — | — | US | claimed |