Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14395280 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2L3MBTL1AHRCHRM2HRH1 | |
| SCHEMBL28655249 | 0.83 | L3MBTL1 (0.45) | SMN1; SMN2L3MBTL1AHRCHRM2BLM | |
| Hydrochloric Acid SCHEMBL9672415 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1AHRCHRM2HRH1 | |
| SCHEMBL10513935 | 0.81 | L3MBTL1 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM2BLM | |
| SCHEMBL24118890 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM2HRH1 | |
| SCHEMBL1478334 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM2HRH1 | |
| SCHEMBL30634160 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1AHRCHRM2HRH1 | |
| SCHEMBL17976467 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1AHRCHRM2NOS3 | |
| SCHEMBL2082803 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1CHRM2HRH1NOS3 | |
| SCHEMBL12934595 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1AHRCHRM2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100393701-C | Process for preparing pyridine-substituted amino ketal derivatives | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-06-11 | — | — | CN | disclosed |
| CN-1747932-A | Process for preparing pyridine substituted amino ketal derivatives | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-03-15 | — | — | CN | disclosed |
| US-6916934-B2 | Process for preparing pyridine-substituted amino ketal derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040158073-A1 | Process for preparing pyridine-substituted amino ketal derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158073-A1 | Process for preparing pyridine-substituted amino ketal derivatives | KMO, PKN1, PKN2 | SMN1; SMN2 1200/4885L3MBTL1 4756/4885AHR 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.