Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4317709 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP3A4GRM2LMNA | |
| SCHEMBL4314804 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP3A4GRM2LMNA | |
| SCHEMBL134600 | 0.96 | ALDH1A1 (0.43) | ALDH1A1TSHRGRM2PREPMEN1 | |
| SCHEMBL131142 | 0.96 | ALDH1A1 (0.43) | ALDH1A1TSHRGRM2PREPMEN1 | |
| SCHEMBL27449506 | 0.93 | ALDH1A1 (0.45) | ALDH1A1TSHRPREPMEN1KMT2A | |
| SCHEMBL16898052 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TSHRPREP | |
| SCHEMBL16898055 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TSHRPREP | |
| SCHEMBL3945465 | 0.83 | FAAH (0.41) | ALDH1A1PREPKMT2A | |
| SCHEMBL14028930 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRGRM2PREPMEN1 | |
| SCHEMBL14028937 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRGRM2PREPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589216-B2 | Process for preparing N-hydroxyformamido-propyl pyrrolidin compounds and intermediates | NOVARTIS AG (CH) | 2009-09-15 | — | — | US | disclosed |
| US-7589216-B2 | Process for preparing N-hydroxyformamido-propyl pyrrolidin compounds and intermediates | NOVARTIS AG (CH) | 2009-09-15 | — | — | US | disclosed |
| EP-1542968-B1 | PROCESS FOR PREPARING INTERMEDIATES | NOVARTIS AG (CH) | 2008-12-17 | — | — | EP | disclosed |
| EP-1599440-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | Novartis AG (CH) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004076053-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2004-09-10 | — | — | WO | disclosed |