SCHEMBL6474809

SCHEMBL6474809

CC(C)(C)c1cc(C[C]=O)cc(C(C)(C)C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.53
GAA P10253 4/20 0.53
TSHR P16473 3/20 0.53
LMNA P02545 2/20 0.53
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
MAPT P10636 4/20 0.53
MAPK1 P28482 3/20 0.53
CYP1A2 P05177 2/20 0.53
CYP3A4 P08684 2/20 0.53
BLM P54132 2/20 0.53
ATM Q13315 2/20 0.53
HIF1A Q16665 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
USP2 O75604 1/20 0.53
CYP2D6 P10635 1/20 0.53
GMNN O75496 1/20 0.52
GABBR2 O75899 1/20 0.52
TP53 P04637 1/20 0.52
CYP2C9 P11712 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265388 0.81 GAA (0.53) ALDH1A1GAATSHRLMNAKMT2A
SCHEMBL3798584 0.80 ALDH1A1 (0.53) ALDH1A1GAATSHRLMNAKMT2A
SCHEMBL11461405 0.77 ALDH1A1 (0.59) ALDH1A1GAATSHRLMNAKMT2A
SCHEMBL5609769 0.77 ALDH1A1 (0.59) ALDH1A1GAATSHRLMNAKMT2A
SCHEMBL39559 0.76 ALDH1A1 (0.63) ALDH1A1GAATSHRLMNAKMT2A
SCHEMBL284696 0.76 ALDH1A1 (0.63) ALDH1A1GAATSHRLMNAKMT2A
SCHEMBL11470243 0.76 HMGCR (0.51) ALDH1A1GAATSHRLMNAKMT2A
SCHEMBL3110243 0.76 ALDH1A1 (0.49) ALDH1A1GAATSHRLMNAKMT2A
SCHEMBL4194073 0.76 ALDH1A1 (0.53) ALDH1A1GAATSHRLMNAKMT2A
SCHEMBL9338699 0.75 ALDH1A1 (0.57) ALDH1A1GAATSHRLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6867297-B1 Process for synthesizing 4-substituted azetidinone derivatives DAIICHI SUNTORY PHARMA CO., LTD. (JP) 2005-03-15 US disclosed
EP-0638552-B1 PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE DAIICHI SUNTORY PHARMA CO LTD (JP) 2003-06-04 EP disclosed
EP-0638552-A1 PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE SUNTORY LIMITED (JP) 1995-02-15 EP disclosed
EP-0593936-A1 N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-27 EP disclosed
US-4344877-A Bicyclo 4-acyloxypiperidine light stabilizers CIBA-GEIGY CORPORATION (US) 1982-08-17 US disclosed
US-4219465-A Piperidine-spiro-hydantoin derivatives and their use as polymer stabilizers SANKYO COMPANY LIMITED (JP) 1980-08-26 US disclosed
EP-0006536-A1 Piperidine-spiro-hydantoin derivatives and their use as light stabilizers for synthetic polymers SANKYO COMPANY LIMITED (JP) 1980-01-09 EP disclosed
US-4123418-A BIS-(U8I8I8L8L-PENTAMETHY TETRAMETHYL-4-PIPERIDYL)-SUBERATE CIBA-GEIGY CORPORATION (US) 1978-10-31 US disclosed
US-4110304-A STERICALLY HINDERED CYCLIC AMINE CIBA-GEIGY CORPORATION (US) 1978-08-29 US disclosed