Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39028 | 0.79 | ALDH1A1 (0.57) | ALDH1A1GAAMAPTTSHRMAPK1 | |
| SCHEMBL38917 | 0.77 | CA2 (0.55) | ALDH1A1GAAMAPTTSHRMAPK1 | |
| SCHEMBL6474809 | 0.76 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTTSHRMAPK1 | |
| SCHEMBL17360017 | 0.76 | GABRA1 (0.41) | HMGCRPOLB | |
| SCHEMBL11650738 | 0.76 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTTSHRMAPK1 | |
| SCHEMBL27621538 | 0.76 | ALDH1A1 (0.53) | ALDH1A1GAAMAPTTSHRMAPK1 | |
| SCHEMBL25310165 | 0.75 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTTSHRMAPK1 | |
| SCHEMBL6060698 | 0.75 | HMGCR (0.55) | ALDH1A1GAAMAPTTSHRMAPK1 | |
| SCHEMBL21221887 | 0.75 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTTSHRMAPK1 | |
| SCHEMBL21986488 | 0.75 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234930-A | Treating psychological, cardiovascular, urogenital and respiratory disorders; diabetes, asthmas, sudden infant death syndrome | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | claimed |
| US-4185014-A | Kentenimine intermediates for 6α-methoxy-α-carboxy penicillins | BEECHAM GROUP LIMITED (GB) | 1980-01-22 | — | — | US | claimed |
| EP-1556389-B9 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2015-09-09 | — | — | EP | disclosed |
| EP-1556389-B3 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2015-04-01 | — | — | EP | disclosed |
| EP-1663245-B1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-20090012054-A1 | Cephem Compounds and Use as Antimicrobial Agents | ASTELLAS PHARMA INC. (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1556389-B1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2007-07-25 | — | — | EP | disclosed |
| US-7192943-B2 | Cephem compounds | ASTELLAS PHARMA INC. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20070037786-A1 | Cephem compounds | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| US-7129232-B2 | For therapy of of infectious diseases | ASTELLAS PHARMA INC. (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20050096306-A1 | Cephem compounds | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| US-4234578-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1980-11-18 | — | — | US | disclosed |
| US-4202973-A | Ketenimine cephalosporins | BEECHAM GROUP LIMITED (GB) | 1980-05-13 | — | — | US | disclosed |
| US-4198406-A | Carbamoyl heterocyclicthio cephalosporins and pharmaceutical compositions formulated therewith | BEECHAM GROUP LIMITED (GB) | 1980-04-15 | — | — | US | disclosed |
| US-4185014-A | Kentenimine intermediates for 6α-methoxy-α-carboxy penicillins | BEECHAM GROUP LIMITED (GB) | 1980-01-22 | — | — | US | disclosed |
| US-4182710-A | Ketenimine intermediates for 6α-methoxy-α-carboxy penicillins | BEECHAM GROUP LIMITED (GB) | 1980-01-08 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| EP-0000644-A2 | Lower cycloalkyl substituted-benzene derivatives, the preparation thereof and their pharmaceutical compositions | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-02-07 | — | — | EP | disclosed |
| US-4024249-A | FOR COMBATTING MICROORGANISMS | CIBA-GEIGY CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3988467-A | Aminoacyl compounds | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037786-A1 | Cephem compounds | CEP170, ABCB11, SLC7A1 | ALDH1A1 1158/4885GAA 3656/4885MAPT 2537/4885 |
| US-20050096306-A1 | Cephem compounds | CEP170, ASS1, C1S | ALDH1A1 1854/4885GAA 3639/4885MAPT 3569/4885 |
| US-20090012054-A1 | Cephem Compounds and Use as Antimicrobial Agents | CEP170, Q6ZSR9, H1-10 | ALDH1A1 3781/4885GAA 4701/4885MAPT 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.