Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647484 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL6675232 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL6675229 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL645501 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL645499 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL9440557 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL9440571 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL2290699 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL646616 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL646614 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12383476-B2 | W/O/W emulsion composition | SHISEIDO COMPANY, LTD. (JP) | 2025-08-12 | — | — | US | disclosed |
| WO-2024142892-A1 | W/O/W EMULSIFIED COMPOSITION | 株式会社 資生堂 | 2024-07-04 | — | — | WO | disclosed |
| WO-2024142969-A1 | WATER-IN-OIL EMULSION COMPOSITION | 株式会社 資生堂 | 2024-07-04 | — | — | WO | disclosed |
| WO-2024080367-A1 | POLYSILOXANE-COATED METAL OXIDE PARTICLES, DISPERSION LIQUID, COMPOSITION, COSMETIC, AND METHOD FOR PRODUCING POLYSILOXANE-COATED METAL OXIDE PARTICLES | 住友大阪セメント株式会社 | 2024-04-18 | — | — | WO | disclosed |
| WO-2023210618-A1 | SURFACE-TREATED ZINC OXIDE PARTICLES, DISPERSION LIQUID, COSMETIC MATERIAL, METHOD FOR PRODUCING SURFACE-TREATED ZINC OXIDE PARTICLES | 住友大阪セメント株式会社 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023190487-A1 | SURFACE-MODIFIED ZINC OXIDE PARTICLES, DISPERSION LIQUID AND COSMETIC PREPARATION | 住友大阪セメント株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023145102-A1 | ZINC OXIDE POWDER, LIQUID DISPERSION, COATING MATERIAL, AND COSMETIC | 住友大阪セメント株式会社 | 2023-08-03 | — | — | WO | disclosed |
| US-20220362112-A1 | W/O/W EMULSION COMPOSITION | SHISEIDO COMPANY, LTD. (JP) | 2022-11-17 | — | — | US | disclosed |
| US-20180161255-A1 | SILICON OXIDE-COATED ZINC OXIDE, COMPOSITION CONTAINING SILICON OXIDE-COATED ZINC OXIDE, AND COSMETIC PRODUCT | SUMITOMO OSAKA CEMENT CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| EP-1974717-B1 | DISPERSION OF FINE TITANIUM OXIDE PARTICLES AND COSMETIC PREPARATION CONTAINING THE SAME | SHISEIDO CO LTD (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-8119108-B2 | Dispersion of microparticulate titanium oxide and cosmetics containing the same | SHISEIDO CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20090169496-A1 | Dispersion Of Microparticulate Titanium Oxide And Cosmetics Containing The Same | SHISEIDO CO., LTD. (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1974717-A1 | DISPERSION OF FINE TITANIUM OXIDE PARTICLES AND COSMETIC PREPARATION CONTAINING THE SAME | Shiseido Company, Limited (JP) | 2008-10-01 | — | — | EP | disclosed |
| EP-0350314-B1 | Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. | SHISEIDO CO LTD (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5093511-A | SILICONE TYPE CINNAMIC ACID DERIVATIVE, PREPARATION METHOD THEREOF, UV-RAY ABSORBER, AND EXTERNAL SKIN TREATMENT AGENT | SHISEIDO COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0350314-A2 | Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. | SHISEIDO COMPANY LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169496-A1 | Dispersion Of Microparticulate Titanium Oxide And Cosmetics Containing The Same | THPO, TPSD1, TPSG1 | KDM4E 2562/4885ALDH1A1 4588/4885HPGD 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.