SCHEMBL6675232

SCHEMBL6675232

COc1cc(C=CC(=O)O)c(CCC(C)C[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C)c(OC)c1OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.39
ALDH1A1 P00352 10/20 0.39
HPGD P15428 5/20 0.39
HSD17B10 Q99714 2/20 0.39
HTR1A P08908 1/20 0.39
HTR2C P28335 1/20 0.39
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 2/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6675229 1.00 KDM4E (0.39) KDM4EALDH1A1HPGDHSD17B10HTR1A
SCHEMBL647484 0.86 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10HTR1A
SCHEMBL647486 0.86 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10HTR1A
SCHEMBL645501 0.85 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10HTR1A
SCHEMBL645499 0.85 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10HTR1A
SCHEMBL9440557 0.84 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10HTR1A
SCHEMBL9440571 0.84 KDM4E (0.41) KDM4EALDH1A1HPGDHSD17B10HTR1A
SCHEMBL2290699 0.80 KDM4E (0.51) KDM4EALDH1A1HPGDHSD17B10HTR1A
SCHEMBL647361 0.79 KDM4E (0.40) KDM4EALDH1A1HPGDHSD17B10HTR1A
SCHEMBL647363 0.79 KDM4E (0.40) KDM4EALDH1A1HPGDHSD17B10HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772224-B2 Perfuming solution stabilized with respect to ultraviolet radiation LVMH RECHERCHE (FR) 2014-07-08 US claimed
US-20130045913-A1 PERFUMING SOLUTION STABILIZED WITH RESPECT TO ULTRAVIOLET RADIATION LVMH RECHERCHE (FR) 2013-02-21 US claimed
US-10463604-B2 Skincare and/or make-up method providing protection against UV rays LVMH RECHERCHE (FR) 2019-11-05 US disclosed
US-9624431-B2 Anti-ultraviolet additive comprising a UVA filter, a UVB filter and an oil that is a solvent for said filters, and use thereof in coloured and/or perfumed compositions LVMH RECHERCHE (FR) 2017-04-18 US disclosed
US-20140252283-A1 ANTI-ULTRAVIOLET ADDITIVE COMPRISING A UVA FILTER, A UVB FILTER AND AN OIL THAT IS A SOLVENT FOR SAID FILTERS, AND USE THEREOF IN COLOURED AND/OR PERFUMED COMPOSITIONS LVMH RECHERCHE (FR) 2014-09-11 US disclosed
US-8771653-B2 Anti-ultraviolet additive comprising a UVA filter, a UVB filter and an oil that is a solvent for said filters, and use thereof in coloured and/or perfumed compositions LVMH RECHERCHE (FR) 2014-07-08 US disclosed
US-8772224-B2 Perfuming solution stabilized with respect to ultraviolet radiation LVMH RECHERCHE (FR) 2014-07-08 US disclosed
US-20130046029-A1 ANTI-ULTRAVIOLET ADDITIVE COMPRISING A UVA FILTER, A UVB FILTER AND AN OIL THAT IS A SOLVENT FOR SAID FILTERS, AND USE THEREOF IN COLOURED AND/OR PERFUMED COMPOSITIONS LVMH RECHERCHE (FR) 2013-02-21 US disclosed
US-20130045913-A1 PERFUMING SOLUTION STABILIZED WITH RESPECT TO ULTRAVIOLET RADIATION LVMH RECHERCHE (FR) 2013-02-21 US disclosed
EP-0955035-B1 Method of preventing aged body odor SHISEIDO CO LTD (JP) 2004-09-29 EP disclosed
EP-0955035-A1 Body odor preventing composition SHISEIDO COMPANY LIMITED (JP) 1999-11-10 EP disclosed
US-5315022-A Sunscreen SHISEIDO COMPANY LTD. (JP) 1994-05-24 US disclosed