Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | MAX | P61244 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293244 | 0.79 | CXCR2 (0.59) | CDK2POLBKMT2AMEN1CXCR2 | |
| SCHEMBL6474951 | 0.79 | MEN1 (0.61) | CDK2FFAR1POLBKMT2AMEN1 | |
| SCHEMBL16862346 | 0.79 | KMT2A (0.56) | CDK2POLBKMT2AMEN1CXCR2 | |
| SCHEMBL6475590 | 0.76 | KMT2A (0.50) | CDK2POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL2443092 | 0.75 | TSHR (0.50) | CDK2POLBKMT2AMEN1CXCR2 | |
| SCHEMBL16737117 | 0.75 | MAPT (0.51) | CDK2POLBKMT2AMEN1CXCR2 | |
| SCHEMBL12086509 | 0.75 | TSHR (0.50) | CDK2POLBKMT2AMEN1CXCR2 | |
| SCHEMBL16737201 | 0.75 | TSHR (0.50) | CDK2POLBKMT2AMEN1CXCR2 | |
| SCHEMBL6484033 | 0.74 | KMT2A (0.43) | CDK2POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL7499740 | 0.74 | MEN1 (0.64) | KMT2AMEN1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972287-B1 | Method of inhibiting amyloid protein aggregation and imaging amyloid deposits | PFIZER INC. (US) | 2005-12-06 | — | — | US | claimed |