Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 7/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691801 | 0.89 | RIPK2 (0.52) | RIPK2TSHRSCN9ALMNARAB9A | |
| SCHEMBL8044057 | 0.86 | RIPK2 (0.50) | RIPK2TSHRSCN9ALMNARAB9A | |
| SCHEMBL11039372 | 0.84 | SCN9A (0.52) | SCN9AALDH1A1LMNARAB9ACNR1 | |
| SCHEMBL8049323 | 0.83 | SCN9A (0.54) | RIPK2TSHRSCN9ALMNARAB9A | |
| SCHEMBL8047290 | 0.83 | RIPK2 (0.50) | RIPK2TSHRSCN9ALMNARAB9A | |
| SCHEMBL1691442 | 0.82 | RIPK2 (0.63) | RIPK2TSHRSCN9AALDH1A1LMNA | |
| SCHEMBL10850115 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNARAB9ASMN1; SMN2CNR1 | |
| SCHEMBL31117084 | 0.81 | HTT (0.69) | TSHRSCN9AALDH1A1LMNARAB9A | |
| SCHEMBL6476731 | 0.81 | MAPK1 (0.56) | RIPK2TSHRLMNARAB9ASMN1; SMN2 | |
| SCHEMBL10340615 | 0.81 | ALDH1A1 (0.48) | TSHRALDH1A1LMNASMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209251-A1 | Substituted pyrazolo-pyrimidine-4-ones | BAYER CROPSCIENCE AG (DE) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209251-A1 | Substituted pyrazolo-pyrimidine-4-ones | P2RX4, DHFR, DDT | RIPK2 3879/4885TSHR 848/4885SCN9A 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.