Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6477062 | 0.75 | HPGD (0.43) | MEN1KMT2AALOX5PTGS1 | |
| SCHEMBL5281256 | 0.75 | ALOX5 (0.43) | MEN1KMT2AALOX5PTGS1 | |
| SCHEMBL6475630 | 0.74 | ALOX5 (0.45) | MEN1KMT2AALOX5PTGS1 | |
| SCHEMBL6487543 | 0.69 | ALOX5 (0.39) | MEN1KMT2AALOX5PTGS1 | |
| SCHEMBL8844254 | 0.67 | KDM4E (0.40) | MEN1KMT2APTGS1 | |
| SCHEMBL3728321 | 0.64 | KDM4E (0.58) | MEN1KMT2ABACE1NPC1PTGS1 | |
| SCHEMBL10496442 | 0.64 | BACE1 (0.63) | MEN1KMT2ABACE1ALOX5NPC1 | |
| SCHEMBL3273499 | 0.64 | BACE1 (0.75) | MEN1KMT2ABACE1NPC1POLB | |
| SCHEMBL3782026 | 0.64 | BACE1 (0.55) | MEN1KMT2ABACE1NPC1POLB | |
| SCHEMBL1514634 | 0.64 | KMT2A (0.76) | MEN1KMT2AALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936632-B2 | Fused pyrrole compounds, pharmaceutical agents containing the same, and the use thereof | MERCKLE GMBH (DE) | 2005-08-30 | — | — | US | disclosed |