SCHEMBL6475704

SCHEMBL6475704

O=C(O)CCc1ccc(OCC=C(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 9/20 0.72
FFAR1 O14842 7/20 0.55
FFAR4 Q5NUL3 3/20 0.55
PPARG P37231 6/20 0.50
PPARA Q07869 6/20 0.50
MAOB P27338 2/20 0.48
PDPK1 O15530 1/20 0.46
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6482981 0.88 PPARD (0.70) PPARDPPARGPPARAMAOB
SCHEMBL6474332 0.86 PPARD (0.77) PPARDFFAR1FFAR4PPARGPPARA
SCHEMBL6482041 0.84 PPARD (0.77) PPARDFFAR1FFAR4PPARGPPARA
SCHEMBL6474183 0.84 PPARD (0.77) PPARDFFAR1FFAR4PPARGPPARA
SCHEMBL6480506 0.84 PPARD (1.00) PPARDFFAR1FFAR4PPARGPPARA
SCHEMBL6527568 0.82 PPARD (0.75) PPARDFFAR1FFAR4PPARGPPARA
SCHEMBL5959443 0.81 PPARD (0.59) PPARDPPARGPPARA
SCHEMBL6474386 0.81 PPARD (0.73) PPARDFFAR1FFAR4PPARGPPARA
SCHEMBL6480530 0.78 PPARD (0.65) PPARDFFAR1FFAR4PPARGPPARA
SCHEMBL117230 0.78 FFAR1 (0.73) FFAR1FFAR4PPARAPDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6869967-B2 Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives NOVO NORDISK A/S (DK) 2005-03-22 US claimed
US-20030139473-A1 Novel compounds, their preparation and use VTVX HOLDINGS II LLC 2003-07-24 US claimed
US-6869967-B2 Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives NOVO NORDISK A/S (DK) 2005-03-22 US disclosed
US-20030139473-A1 Novel compounds, their preparation and use VTVX HOLDINGS II LLC 2003-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139473-A1 Novel compounds, their preparation and use PPARG, PPARD, PPARA PPARD 2/4885FFAR1 22/4885FFAR4 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.