Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476542 | 0.91 | MEN1 (0.45) | CNR2MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4249115 | 0.79 | NPC1 (0.50) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL11689679 | 0.79 | NPC1 (0.50) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL4897611 | 0.78 | TP53 (0.47) | ALDH1A1TSHRLTB4R2TP53 | |
| SCHEMBL6474913 | 0.74 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL1668024 | 0.73 | TP53 (0.53) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL14174039 | 0.73 | CNR2 (0.67) | CNR2TSHRAOC3CHRM2HTR1A | |
| SCHEMBL11690630 | 0.72 | LTB4R2 (0.48) | CNR2SMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL6475710 | 0.72 | CLCN2 (0.49) | CNR2MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28860869 | 0.72 | TSHR (0.58) | CNR2MEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972287-B1 | Method of inhibiting amyloid protein aggregation and imaging amyloid deposits | PFIZER INC. (US) | 2005-12-06 | — | — | US | claimed |