Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 2/20 | 0.49 |
| ▸ | PLK1 | P53350 | 4/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474913 | 0.88 | MEN1 (0.55) | CLCN2PLK1PLK3ABCC1TRPA1 | |
| SCHEMBL6486927 | 0.86 | CLCN2 (0.46) | CLCN2PLK1SLC16A3PLK3ABCC1 | |
| SCHEMBL6474928 | 0.83 | SIRT1 (0.50) | CLCN2PLK1PLK3MEN1KMT2A | |
| SCHEMBL6474259 | 0.83 | MEN1 (0.60) | CLCN2PLK1MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL6474052 | 0.81 | MEN1 (0.58) | CLCN2PLK1MEN1KMT2ATDP1 | |
| SCHEMBL6482938 | 0.79 | MEN1 (0.53) | CLCN2PLK1PLK3ABCC1TRPA1 | |
| SCHEMBL6475251 | 0.79 | MEN1 (0.56) | CLCN2PLK1PLK3ABCC1MEN1 | |
| SCHEMBL6486359 | 0.78 | PLK1 (0.53) | CLCN2PLK1PLK3TRPA1TRPM2 | |
| SCHEMBL6486936 | 0.78 | MEN1 (0.48) | CLCN2PLK1SLC16A3PLK3MEN1 | |
| SCHEMBL4249109 | 0.77 | PLK1 (0.60) | CLCN2PLK1SLC16A3PLK3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972287-B1 | Method of inhibiting amyloid protein aggregation and imaging amyloid deposits | PFIZER INC. (US) | 2005-12-06 | — | — | US | claimed |