Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11689679 | 0.88 | NPC1 (0.50) | TP53ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL4249115 | 0.88 | NPC1 (0.50) | TP53ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL15640142 | 0.82 | LTB4R2 (0.46) | TP53ALDH1A1RXRARXRBRXRG | |
| SCHEMBL7153294 | 0.82 | DHFR (0.43) | TP53MTNR1AMTNR1BALDH1A1RXRA | |
| SCHEMBL4086031 | 0.81 | TP53 (0.52) | TP53ALDH1A1ALOX15KDM4EPOLB | |
| SCHEMBL14399055 | 0.80 | PTPN1 (0.43) | TP53MTNR1AMTNR1BALDH1A1ALOX15 | |
| SCHEMBL341927 | 0.79 | ALDH1A1 (0.45) | MTNR1AMTNR1BALDH1A1ALOX15KDM4E | |
| SCHEMBL3514125 | 0.79 | GAA (0.44) | TP53ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL5515003 | 0.78 | TP53 (0.49) | TP53ALDH1A1ALOX15TSHRPTPN1 | |
| SCHEMBL6475705 | 0.78 | CNR2 (0.46) | TP53ALDH1A1TSHRLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103205-A1 | Pesticidal compositions and methods of use | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2008-05-01 | — | — | US | disclosed |
| WO-2007050867-A2 | PESTICIDAL COMPOSITIONS AND METHODS OF USE | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103205-A1 | Pesticidal compositions and methods of use | SLC47A1, SLC22A8, SLC47A2 | TP53 3963/4885MTNR1A 2500/4885MTNR1B 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.