SCHEMBL4249109

SCHEMBL4249109

CCCCCCCCCCc1ccccc1Nc1ccccc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 4/20 0.60
CLCN2 P51788 1/20 0.58
PLK3 Q9H4B4 3/20 0.57
SLC16A3 O15427 7/20 0.55
BID P55957 3/20 0.50
MCL1 Q07820 3/20 0.50
BCL2L1 Q07817 2/20 0.50
BAK1 Q16611 2/20 0.50
KAT8 Q9H7Z6 2/20 0.50
MAPK8 P45983 1/20 0.50
FABP4 P15090 1/20 0.50
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50
EP300 Q09472 1/20 0.50
KAT2A Q92830 1/20 0.50
KAT2B Q92831 1/20 0.50
KAT5 Q92993 1/20 0.50
SAE1 Q9UBE0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10868916 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL3205158 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL31139998 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL10869653 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL9418574 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL2492910 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL1567827 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL29785474 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL14785526 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL3202309 0.84 LIPG (0.56) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090131527-A1 NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-05-21 US claimed
US-20090131527-A1 NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131527-A1 NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME CLIC1, ASIC1, CLIC4 PLK1 2146/4885CLCN2 5/4885PLK3 3463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.