Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 14/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474742 | 0.91 | KCNA3 (0.39) | KCNA3MMP1EPHX2POLBHTT | |
| SCHEMBL6483520 | 0.89 | GAA (0.42) | EPHX2POLBHTTNPSR1L3MBTL1 | |
| SCHEMBL6474636 | 0.87 | LPAR1 (0.36) | KCNA3EPHX2POLBHTTNPSR1 | |
| SCHEMBL6476219 | 0.87 | ALDH1A1 (0.45) | POLBHTTNPSR1L3MBTL1 | |
| SCHEMBL6482260 | 0.86 | ALDH1A1 (0.37) | KCNA3POLBHTTNPSR1L3MBTL1 | |
| SCHEMBL6482572 | 0.86 | MEN1 (0.39) | KCNA3EPHX2POLBHTTNPSR1 | |
| SCHEMBL6482268 | 0.85 | ALDH1A1 (0.46) | L3MBTL1 | |
| SCHEMBL6474377 | 0.85 | ALDH1A1 (0.46) | L3MBTL1 | |
| SCHEMBL6484134 | 0.85 | ALDH1A1 (0.46) | L3MBTL1 | |
| SCHEMBL7675801 | 0.84 | EPHX2 (0.37) | KCNA3EPHX2POLBHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939888-B2 | 1-H-3-arylpirrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-06 | — | — | US | disclosed |
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | FISCHER REINER (DE) | 2004-01-29 | — | — | US | disclosed |
| US-6472419-B1 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | PRXL2A, DDT, CYP4B1 | KCNA3 1788/4885MMP1 3464/4885EPHX2 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.