Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3046550 | 0.99 | KMT2A (0.56) | KMT2AMEN1MAPTADORA2AADORA1 | |
| SCHEMBL5036546 | 0.92 | HDAC1 (0.54) | KMT2AMEN1MAPTADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL3048068 | 0.91 | HDAC1 (0.54) | KMT2AMEN1MAPTADORA2AADORA1 | |
| SCHEMBL6485716 | 0.91 | HDAC1 (0.54) | KMT2AMEN1MAPTADORA2AADORA1 | |
| SCHEMBL3039082 | 0.91 | HDAC1 (0.53) | KMT2AMEN1MAPTADORA2AADORA1 | |
| SCHEMBL6481675 | 0.91 | ALK (0.54) | MAPTADORA2AADORA1ADORA2BHDAC1 | |
| Hydrochloric Acid SCHEMBL3051261 | 0.91 | TRPV4 (0.53) | KMT2AMEN1MAPTADORA2AADORA1 | |
| SCHEMBL6476780 | 0.90 | HDAC1 (0.52) | KMT2AMEN1MAPTADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL3048499 | 0.90 | HDAC1 (0.52) | KMT2AMEN1MAPTADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL3053390 | 0.90 | KIT (0.53) | MAPTADORA2AADORA1ADORA2BHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6963000-B2 | Benzothiazole derivatives with activity as adenosine receptor ligands | HOFFMAN-LA ROCHE INC. (US) | 2005-11-08 | — | — | US | claimed |