Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3769185 | 0.89 | CNR1 (0.46) | HSP90AA1HSP90AB1CNR1CNR2CYP2C19 | |
| SCHEMBL18759138 | 0.86 | ALDH1A1 (0.36) | HSP90AA1HSP90AB1CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL631669 | 0.84 | CNR1 (0.37) | CNR1CNR2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL4802713 | 0.82 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1CYP2C19ALDH1A1ALOX15 | |
| SCHEMBL6470377 | 0.82 | CNR1 (0.38) | CNR1CNR2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL20528313 | 0.82 | HSP90AA1 (0.36) | HSP90AA1CYP2C9ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL10593070 | 0.79 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL12971341 | 0.78 | CYP1A2 (0.37) | CNR1CNR2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL3912943 | 0.78 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL7781942 | 0.77 | HSP90AA1 (0.40) | HSP90AA1CYP2C19ALDH1A1ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-1628962-B1 | Iodopyrazolyl carboxanilides | BAYER IP GMBH (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119682-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2011-05-26 | — | — | US | disclosed |
| US-7906656-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-7906656-B2 | Iodopyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20070082877-A1 | Difluoromethylbenzanilides and use thereof for combating micro-organisms, intermediate products and use thereof | BAYER CORPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
| CN-1791582-A | Iodopyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2006-06-21 | — | — | CN | disclosed |
| CN-1791569-A | Difluoromethylbenzanilides and use thereof for combating micro-organisms, intermediate products and use thereof | BAYER CROPSCIENCE AG (DE) | 2006-06-21 | — | — | CN | disclosed |
| EP-1628962-A1 | IODOPYRAZOLYL CARBOXANILIDES | Bayer CropScience AG (DE) | 2006-03-01 | — | — | EP | disclosed |
| EP-1628948-A1 | DIFLUOROMETHYLBENZANILIDES AND USE THEREOF FOR COMBATING MICRO-ORGANISMS, INTERMEDIATE PRODUCTS AND USE THEREOF | Bayer CropScience AG (DE) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004103953-A1 | DIFLUOROMETHYLBENZANILIDES AND USE THEREOF FOR COMBATING MICRO-ORGANISMS, INTERMEDIATE PRODUCTS AND USE THEREOF | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004103975-A1 | IODOPYRAZOLYL CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124698-A1 | Iodopyrazolyl Carboxanilides | IDH2, ABL1, IDH1 | HSP90AA1 4267/4885HSP90AB1 4278/4885CNR1 277/4885 |
| US-20070082877-A1 | Difluoromethylbenzanilides and use thereof for combating micro-organisms, intermediate products and use thereof | FBL, Q6ZSR9, DDT | HSP90AA1 4314/4885HSP90AB1 3883/4885CNR1 2618/4885 |
| US-20070066673-A1 | Iodopyrazolyl carboxanilides | Q6ZSR9, C1S, MRPL21 | HSP90AA1 4198/4885HSP90AB1 4202/4885CNR1 836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.