Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759138 | 0.83 | ALDH1A1 (0.36) | HSP90AA1CYP3A4ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL647668 | 0.82 | HSP90AA1 (0.38) | HSP90AA1CYP3A4ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL7781942 | 0.79 | HSP90AA1 (0.40) | HSP90AA1CYP3A4ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL29470925 | 0.78 | PGR (0.46) | CYP3A4ALOX15SMN1; SMN2CASP1CASP7 | |
| SCHEMBL168119 | 0.78 | CYP3A4 (0.43) | CYP3A4ALOX15SMN1; SMN2CASP1CASP7 | |
| SCHEMBL79300 | 0.78 | PGR (0.46) | CYP3A4ALOX15SMN1; SMN2CASP1CASP7 | |
| SCHEMBL3641431 | 0.77 | GABRA1 (0.42) | HSP90AA1ALDH1A1TSHRTDP1PGR | |
| SCHEMBL4802713 | 0.76 | HSP90AA1 (0.42) | HSP90AA1CYP3A4ALOX15SMN1; SMN2CASP1 | |
| SCHEMBL3546505 | 0.76 | CHRM3 (0.35) | CYP3A4ALOX15SMN1; SMN2CASP1CASP7 | |
| SCHEMBL3769185 | 0.76 | CNR1 (0.46) | HSP90AA1ALDH1A1HSD17B10GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141437-B | Crystallization-controllable thermoplastic polyurethane material and preparation method thereof | 万华化学集团股份有限公司 | 2020-03-03 | — | — | CN | claimed |
| US-11286328-B2 | Thermoplastic polyurethane elastomer, and preparation method, use and product thereof | WANHUA CHEMICAL GROUP CO., LTD. | 2022-03-29 | — | — | US | disclosed |
| CN-111087967-A | Polyurethane adhesive, preparation method thereof and filter | 上海汉司实业有限公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-107141437-B | Crystallization-controllable thermoplastic polyurethane material and preparation method thereof | 万华化学集团股份有限公司 | 2020-03-03 | — | — | CN | disclosed |
| US-20180291141-A1 | THERMOPLASTIC POLYURETHANE ELASTOMER, AND PREPARATION METHOD, USE AND PRODUCT THEREOF | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2018-10-11 | — | — | US | disclosed |