Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476772 | 1.00 | USP2 (0.35) | USP2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL28621500 | 0.82 | USP2 (0.38) | USP2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL5176932 | 0.77 | FDPS (0.33) | KMT2ASMN1; SMN2 | |
| SCHEMBL7710676 | 0.76 | KCNA5 (0.32) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL7708081 | 0.76 | KCNA5 (0.32) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL7708077 | 0.76 | KCNA5 (0.32) | ALDH1A1LMNAMAPTHPGDRAB9A | |
| SCHEMBL18922366 | 0.74 | SMN1; SMN2 (0.35) | USP2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL5792071 | 0.73 | MAPT (0.39) | USP2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL3750095 | 0.73 | USP2 (0.38) | USP2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL12497740 | 0.71 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897210-B2 | Quinazoline derivatives and pharmaceutical compositions containing them | ZENECA LIMITED (GB) | 2005-05-24 | — | — | US | disclosed |