Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | F7 | P08709 | 2/20 | 0.37 |
| ▸ | F3 | P13726 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476907 | 1.00 | SOAT2 (0.42) | SOAT2SOAT1EPHX2FAAHCNR1 | |
| SCHEMBL4474820 | 0.83 | SOAT2 (0.44) | SOAT2SOAT1EPHX2FAAHCNR1 | |
| SCHEMBL4474815 | 0.83 | SOAT2 (0.44) | SOAT2SOAT1EPHX2FAAHCNR1 | |
| SCHEMBL4468762 | 0.83 | SOAT2 (0.44) | SOAT2SOAT1EPHX2FAAHCNR1 | |
| SCHEMBL4468757 | 0.83 | SOAT2 (0.44) | SOAT2SOAT1EPHX2FAAHCNR1 | |
| SCHEMBL4468496 | 0.83 | SOAT2 (0.44) | SOAT2SOAT1EPHX2FAAHCNR1 | |
| SCHEMBL4468500 | 0.83 | SOAT2 (0.44) | SOAT2SOAT1EPHX2FAAHCNR1 | |
| SCHEMBL21356899 | 0.81 | SOAT2 (0.43) | SOAT2SOAT1EPHX2FAAHCNR1 | |
| SCHEMBL10490478 | 0.80 | SOAT2 (0.42) | SOAT2SOAT1EPHX2FAAHCNR1 | |
| SCHEMBL10490482 | 0.80 | SOAT2 (0.42) | SOAT2SOAT1EPHX2FAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887863-B2 | Hydrazide and alkoxyamide angiogenesis inhibitors | ABBOTT LABORATORIES (US) | 2005-05-03 | — | — | US | disclosed |
| US-20040167126-A1 | Hydrazide and alkoxyamide angiogenesis inhibitors | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167126-A1 | Hydrazide and alkoxyamide angiogenesis inhibitors | METAP2, METAP1, ANPEP | SOAT2 603/4885SOAT1 1375/4885EPHX2 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.