Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 6/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.40 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BRD1 | O95696 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471808 | 0.90 | DRD2 (0.50) | HTR6LMNAKMT2APAX8USP2 | |
| SCHEMBL6472315 | 0.84 | HTR6 (0.54) | HTR6ALDH1A1 | |
| SCHEMBL4477512 | 0.76 | HSD17B2 (0.42) | HPGDHTR6BRD4KMT2AHSD17B10 | |
| SCHEMBL4496731 | 0.71 | HTR6 (0.45) | HPGDHTR6BRD4LMNAKDM4E | |
| SCHEMBL3357543 | 0.71 | HPGD (0.54) | HPGDHTR6BRD4TRIM24LMNA | |
| SCHEMBL6118790 | 0.69 | HTR6 (0.59) | HPGDHTR6BRD4TRIM24ALDH1A1 | |
| SCHEMBL2170725 | 0.68 | CYP3A4 (0.50) | HTR6BRD4TRIM24LMNAALDH1A1 | |
| SCHEMBL2170411 | 0.68 | CYP3A4 (0.58) | HTR6BRD4TRIM24LMNAALDH1A1 | |
| SCHEMBL2183994 | 0.68 | CYP3A4 (0.49) | HTR6BRD4TRIM24ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6118475 | 0.67 | CYP3A4 (0.48) | HTR6BRD4TRIM24ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037830-A1 | PIPERIDINYLCHROMEN-6-YLSULFONAMIDE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2005-04-28 | — | — | WO | claimed |
| WO-2005037830-A1 | PIPERIDINYLCHROMEN-6-YLSULFONAMIDE COMPOUNDS AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2005-04-28 | — | — | WO | disclosed |