Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 8/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476960 | 1.00 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6484222 | 0.88 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6477263 | 0.81 | PTGS2 (0.71) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6476216 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6477175 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6487417 | 0.77 | PTGS2 (0.62) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6488009 | 0.76 | PTGS2 (0.61) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6487001 | 0.75 | PTGS2 (0.60) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6290043 | 0.75 | PTGS2 (0.62) | PTGS2PTGS1ALOX5 | |
| SCHEMBL6486425 | 0.74 | PTGS2 (0.77) | PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936632-B2 | Fused pyrrole compounds, pharmaceutical agents containing the same, and the use thereof | MERCKLE GMBH (DE) | 2005-08-30 | — | — | US | disclosed |
| EP-1246825-B1 | FUSED PYRROLE COMPOUNDS, PHARMACEUTICAL AGENTS CONTAINING THE SAME, AND THE USE THEREOF | MERCKLE GMBH (DE) | 2003-12-17 | — | — | EP | disclosed |