Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10866338 | 0.82 | TSHR (0.56) | KMT2AMEN1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL4838619 | 0.80 | TSHR (0.57) | KMT2AMEN1ATML3MBTL1ALDH1A1 | |
| SCHEMBL21639478 | 0.78 | MEN1 (0.48) | KMT2AMEN1ATML3MBTL1ALDH1A1 | |
| SCHEMBL12929653 | 0.77 | ALDH1A1 (0.77) | KMT2AMEN1ATML3MBTL1ALDH1A1 | |
| SCHEMBL17595922 | 0.76 | L3MBTL1 (0.58) | KMT2AL3MBTL1ALDH1A1HTTTSHR | |
| SCHEMBL1522806 | 0.76 | L3MBTL1 (0.55) | KMT2AL3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL3516526 | 0.76 | L3MBTL1 (0.55) | KMT2AMEN1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL25728058 | 0.75 | KDM4E (0.57) | KMT2AMEN1ATML3MBTL1ALDH1A1 | |
| SCHEMBL16236403 | 0.75 | L3MBTL1 (0.54) | KMT2AL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL3519261 | 0.75 | L3MBTL1 (0.54) | KMT2AMEN1L3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005107744-A1 | NERVE DAMAGE | ROELANTS, IVO (BE) | 2005-11-17 | — | — | WO | disclosed |