Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167944 | 0.86 | FYN (0.39) | FYNSMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL6472740 | 0.77 | FYN (0.38) | FYNEGFRMEN1NPC1CASP3 | |
| SCHEMBL17589343 | 0.74 | FYN (0.44) | FYNEGFRMEN1NPC1CASP3 | |
| SCHEMBL6473730 | 0.73 | FYN (0.37) | FYNSMN1; SMN2KDM4EEGFRMAOB | |
| SCHEMBL6473343 | 0.73 | FYN (0.37) | FYNSMN1; SMN2KDM4EEGFRMAOB | |
| SCHEMBL6479157 | 0.72 | FYN (0.40) | FYNSMN1; SMN2KDM4EEGFRRAB9A | |
| SCHEMBL17788892 | 0.71 | EGFR (0.56) | FYNEGFRKDM1AHPGD | |
| SCHEMBL7931935 | 0.70 | FYN (0.39) | FYNSMN1; SMN2EGFRMAOBKDM1A | |
| SCHEMBL7931938 | 0.70 | FYN (0.39) | FYNSMN1; SMN2EGFRMAOBKDM1A | |
| SCHEMBL2131789 | 0.70 | ACHE (0.52) | MEN1KMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037756-A2 | NOVEL METHODS FOR THE PREPARATION OF 4-[4-(4-METHOXYMETHOXY-4'-METHYL-BIPHENYL-2-YL)-BUT-3-ENE-(E)-1-YNYL]-BENZOIC ACID | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-04-28 | — | — | WO | claimed |
| WO-2005037756-A2 | NOVEL METHODS FOR THE PREPARATION OF 4-[4-(4-METHOXYMETHOXY-4'-METHYL-BIPHENYL-2-YL)-BUT-3-ENE-(E)-1-YNYL]-BENZOIC ACID | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-04-28 | — | — | WO | disclosed |