Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825585 | 0.83 | HDAC7 (0.41) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL23176110 | 0.81 | ALDH1A1 (0.43) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL10031629 | 0.75 | ALDH1A1 (0.42) | CA1CA2HSD17B10FAAH | |
| SCHEMBL13876693 | 0.75 | ALDH1A1 (0.42) | CA1CA2HSD17B10FAAH | |
| SCHEMBL115663 | 0.75 | ALDH1A1 (0.42) | CA1CA2HSD17B10FAAH | |
| SCHEMBL12841174 | 0.75 | HDAC7 (0.35) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL27791859 | 0.74 | HSD17B10 (0.36) | CA1CA2HSD17B10 | |
| SCHEMBL13328472 | 0.74 | HSD17B10 (0.36) | CA1CA2HSD17B10 | |
| SCHEMBL9966033 | 0.73 | MMP1 (0.50) | CA1CA2HSD17B10 | |
| SCHEMBL3130179 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005054319-A9 | PROCESS FOR THE PREPARATION OF AMPHIPHILIC POLY (N-VINYL-2-PYRROLIDONE) BLOCK COPOLYMERS | LABOPHARM INC (CA) | 2005-09-15 | — | — | WO | claimed |