Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ethyl Oleate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 8/20 | 0.65 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.65 |
| ▸ | MRGPRX2 | Q96LB1 | 3/20 | 0.65 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morphine SCHEMBL6650507 | 0.91 | OPRD1 (0.69) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Morphine SCHEMBL6650502 | 0.91 | OPRD1 (0.69) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL6650505 | 0.88 | OPRD1 (0.62) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Morphine SCHEMBL22234325 | 0.87 | OPRD1 (0.75) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Morphine SCHEMBL3476234 | 0.87 | OPRD1 (0.75) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Morphine SCHEMBL10835255 | 0.85 | OPRD1 (0.73) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Tricaprilin SCHEMBL5669494 | 0.85 | OPRD1 (0.68) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Morphine SCHEMBL547919 | 0.83 | OPRD1 (0.78) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL3476236 | 0.83 | OPRD1 (0.68) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| Morphine SCHEMBL16635671 | 0.81 | OPRD1 (0.85) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050048660-A1 | Biomarker of maternal alcohol use during pregnancy | CASE WESTERN RESERVE UNIVERSITY | 2005-03-03 | — | — | US | disclosed |