Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 3/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6487381 | 0.99 | MEN1 (0.40) | MEN1KMT2ADPP4MGLLCYP1A2 | |
| SCHEMBL6487144 | 0.91 | MEN1 (0.41) | MEN1KMT2ADPP4MGLLLMNA | |
| SCHEMBL6477957 | 0.91 | MEN1 (0.42) | MEN1KMT2ADPP4MGLLCYP1A2 | |
| Hydrochloric Acid SCHEMBL6478389 | 0.90 | MEN1 (0.37) | MEN1KMT2ADPP4MGLLCYP1A2 | |
| Hydrochloric Acid SCHEMBL6479277 | 0.88 | CNR1 (0.42) | MEN1KMT2ADPP4MGLLLMNA | |
| SCHEMBL6488381 | 0.84 | MEN1 (0.40) | MEN1KMT2ADPP4MGLLLMNA | |
| SCHEMBL6479521 | 0.84 | MEN1 (0.48) | MEN1KMT2ADPP4MGLLCYP1A2 | |
| SCHEMBL7488351 | 0.83 | KDM4E (0.46) | MEN1KMT2ADPP4CYP1A2CYP2C9 | |
| SCHEMBL6489868 | 0.82 | SCD (0.45) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6479917 | 0.81 | MEN1 (0.42) | MEN1KMT2ADPP4MGLLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014942-A1 | Transforming growth factor inhibitor; controllign cell differentiation, cell proliferation | NIPPON SHINYAKU CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1452525-A1 | AMIDE DERIVATIVES AND DRUGS | Nippon Shinyaku Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014942-A1 | Transforming growth factor inhibitor; controllign cell differentiation, cell proliferation | TGFBR1, TGFBR2, TGFB1 | MEN1 1774/4885KMT2A 1575/4885DPP4 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.