Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 9/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.42 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041964 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL3064605 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL12640340 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27487445 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL7826195 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6623121 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL5173732 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| Potassium Ion SCHEMBL7826197 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1SIGMAR1L3MBTL3L3MBTL1 | |
| SCHEMBL3774050 | 0.80 | KDM4E (0.73) | KDM4EALDH1A1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL1258251 | 0.80 | GAA (0.56) | KDM4EALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949541-B2 | Substituted piperidines, medicaments containing these compounds, and methods for the production thereof | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-09-27 | — | — | US | claimed |
| US-20030212057-A1 | Substituted piperidines, medicaments containing these compounds, and methods for the production thereof | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-11-13 | — | — | US | claimed |
| US-6949541-B2 | Substituted piperidines, medicaments containing these compounds, and methods for the production thereof | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-09-27 | — | — | US | disclosed |
| US-20030212057-A1 | Substituted piperidines, medicaments containing these compounds, and methods for the production thereof | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212057-A1 | Substituted piperidines, medicaments containing these compounds, and methods for the production thereof | CALCA, CALCRL, P2RY1 | KDM4E 4675/4885ALDH1A1 312/4885SIGMAR1 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.