Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28988173 | 0.96 | DNM1 (0.45) | THRBDNM1MEN1KMT2ATP53 | |
| SCHEMBL14409026 | 0.94 | THRB (0.49) | THRBDNM1MEN1KMT2ATP53 | |
| Sulfuric Acid SCHEMBL2793229 | 0.93 | THRB (0.46) | THRBDNM1MEN1KMT2ATP53 | |
| Bromide SCHEMBL28532164 | 0.92 | DNM1 (0.49) | THRBDNM1MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL3910414 | 0.92 | TP53 (0.49) | THRBDNM1MEN1KMT2ATP53 | |
| Iodide SCHEMBL28537835 | 0.92 | THRB (0.48) | THRBDNM1MEN1KMT2ATP53 | |
| Fluoride Ion SCHEMBL28525852 | 0.92 | THRB (0.48) | THRBDNM1MEN1KMT2ATP53 | |
| SCHEMBL28988183 | 0.91 | DNM1 (0.42) | THRBDNM1MEN1KMT2ATP53 | |
| Sulfuric Acid SCHEMBL28988171 | 0.90 | DNM1 (0.46) | THRBDNM1MEN1KMT2ATP53 | |
| Sulfuric Acid SCHEMBL2976040 | 0.89 | THRB (0.45) | THRBDNM1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005075531-A1 | AMPHIPHILIC BLOCK AND GRAFT COPOLYMERS CONTAINING HEAVY ELEMENTS, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS X-RAY CONTRAST AGENTS | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2005-08-18 | — | — | WO | disclosed |