Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 1.00 |
| ▸ | DRD3 | P35462 | 5/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 4/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 4/20 | 1.00 |
| ▸ | HRH1 | P35367 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | DRD2 | P14416 | 3/20 | 0.97 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.97 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.97 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.97 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.97 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.97 |
| ▸ | HRH2 | P25021 | 2/20 | 0.97 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.97 |
| ▸ | HTR2A | P28223 | 2/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Difluorobenztropine SCHEMBL23675084 | 1.00 | SLC6A3 (1.00) | SLC6A3DRD3CHRM1SLC6A2HRH1 | |
| Difluorobenztropine SCHEMBL2615300 | 1.00 | SLC6A3 (1.00) | SLC6A3DRD3CHRM1SLC6A2HRH1 | |
| Difluorobenztropine SCHEMBL2615298 | 1.00 | SLC6A3 (1.00) | SLC6A3DRD3CHRM1SLC6A2HRH1 | |
| Difluorobenztropine SCHEMBL6676045 | 0.98 | SLC6A3 (1.00) | SLC6A3DRD3CHRM1SLC6A2HRH1 | |
| Difluorobenztropine SCHEMBL6677276 | 0.98 | SLC6A3 (1.00) | SLC6A3DRD3CHRM1SLC6A2HRH1 | |
| Difluorobenztropine SCHEMBL6676047 | 0.98 | SLC6A3 (1.00) | SLC6A3DRD3CHRM1SLC6A2HRH1 | |
| SCHEMBL2615299 | 0.94 | CHRM1 (0.89) | SLC6A3DRD3CHRM1SLC6A2HRH1 | |
| SCHEMBL2615297 | 0.94 | CHRM1 (0.89) | SLC6A3DRD3CHRM1SLC6A2HRH1 | |
| SCHEMBL1152029 | 0.84 | DRD3 (1.00) | SLC6A3DRD3CHRM1SLC6A2HRH1 | |
| SCHEMBL5096472 | 0.84 | DRD3 (1.00) | SLC6A3DRD3CHRM1SLC6A2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005107467-A2 | COMPOSITIONS INCLUDING OPIOIDS AND METHODS OF THEIR USE IN TREATING PAIN | DESCARTES THERAPEUTICS, INC. (US) | 2005-11-17 | — | — | WO | claimed |
| US-9034798-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-8569481-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | KOESTER HUBERT | 2011-05-19 | — | — | US | disclosed |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-20100248264-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-09-30 | — | — | US | disclosed |
| WO-2005107467-A2 | COMPOSITIONS INCLUDING OPIOIDS AND METHODS OF THEIR USE IN TREATING PAIN | DESCARTES THERAPEUTICS, INC. (US) | 2005-11-17 | — | — | WO | disclosed |
| US-5792775-A | HIGH AFFINITY FOR DOPAMINE TRANSPORTER; INHIBIT DOPAMINE UPTAKE; DO NOT HAVE A COCAINE-LIKE BEHAVORIAL PROFILE; USED TO IMAGE BINDING SITES; DIAGNOSIS AND MONITORING OF NEURODEGENERATIVE DISEASES, E.G PARKINSON'S | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PTMS, QPCTL, SRMS | SLC6A3 4328/4885DRD3 3548/4885CHRM1 4772/4885 |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CHLSN, PTMS, SRMS | SLC6A3 4606/4885DRD3 3965/4885CHRM1 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.