Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454786 | 0.79 | POLB (0.34) | HSD17B10ALDH1A1MAPTKDM4E | |
| SCHEMBL11704413 | 0.77 | CA12 (0.31) | — | |
| SCHEMBL6932331 | 0.76 | AR (0.51) | ARALDH1A1MAPTIMPDH2IMPDH1 | |
| SCHEMBL10683512 | 0.74 | ALDH1A1 (0.34) | ARHSD17B10ALDH1A1MAPTKDM4E | |
| SCHEMBL27999345 | 0.73 | HTR2A (0.40) | — | |
| SCHEMBL5512502 | 0.73 | MAOB (0.50) | ARALDH1A1MAPT | |
| SCHEMBL6479477 | 0.71 | AR (0.32) | ARUSP2 | |
| SCHEMBL8565328 | 0.71 | AR (0.41) | ARHSD17B10ALDH1A1MAPTKDM4E | |
| SCHEMBL11884751 | 0.71 | USP2 (0.32) | USP2 | |
| SCHEMBL233007 | 0.71 | ALDH1A1 (0.44) | ARALDH1A1IMPDH2IMPDH1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050153996-A1 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS FOR THEIR PREPARATION | AUERBACH BRUCE J (US) | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153996-A1 | COMPOUNDS THAT MODULATE PPAR ACTIVITY AND METHODS FOR THEIR PREPARATION | GPR119, PPARA, PPARG | AR 569/4885CASP1 3306/4885HSD17B10 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.