Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480835 | 1.00 | ADRB3 (0.61) | ADRB3ADRB1ADRB2SLC2A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6480583 | 0.99 | ADRB3 (0.61) | ADRB3ADRB1ADRB2SLC2A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6480588 | 0.99 | ADRB3 (0.61) | ADRB3ADRB1ADRB2SLC2A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6488290 | 0.91 | ADRB3 (0.71) | ADRB3ADRB1ADRB2SLC2A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6488285 | 0.91 | ADRB3 (0.71) | ADRB3ADRB1ADRB2SLC2A1CYP2D6 | |
| SCHEMBL6479562 | 0.91 | ADRB3 (0.61) | ADRB3ADRB1ADRB2SLC2A1CYP2D6 | |
| SCHEMBL6479579 | 0.91 | ADRB3 (0.61) | ADRB3ADRB1ADRB2SLC2A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6479555 | 0.90 | ADRB3 (0.60) | ADRB3ADRB1ADRB2SLC2A1CYP2D6 | |
| Oxalic Acid SCHEMBL6479546 | 0.87 | ADRB3 (0.58) | ADRB3ADRB1ADRB2SLC2A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL6479347 | 0.87 | ADRB3 (0.48) | ADRB3ADRB1ADRB2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-02-24 | — | — | US | disclosed |
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143034-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB1, ADRB2, ADRB3 | ADRB3 3/4885ADRB1 1/4885ADRB2 2/4885 |
| US-20050043358-A1 | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists | ADRB2, ADRB1, ADRB3 | ADRB3 3/4885ADRB1 2/4885ADRB2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.