Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479386 | 0.85 | AOC3 (0.70) | AOC3SLC6A2SLC6A4SLC6A3CACNA1F | |
| SCHEMBL6742350 | 0.85 | AOC3 (1.00) | AOC3SLC6A2SLC6A4POLBALDH1A1 | |
| SCHEMBL6826544 | 0.81 | AOC3 (0.60) | AOC3ALDH1A1MAPT | |
| SCHEMBL6745741 | 0.81 | AOC3 (0.69) | AOC3SLC6A2SLC6A4SLC6A3CACNA1F | |
| Hydrochloric Acid SCHEMBL14775340 | 0.80 | AOC3 (0.58) | AOC3SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL327629 | 0.79 | AOC3 (0.63) | AOC3ALDH1A1MAPT | |
| SCHEMBL6282443 | 0.79 | AOC3 (0.77) | AOC3SLC6A2SLC6A4HTR2A | |
| SCHEMBL6317820 | 0.79 | AOC3 (0.49) | AOC3SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL11098258 | 0.78 | AOC3 (0.51) | AOC3SLC6A2SLC6A4SLC6A3CACNA1F | |
| SCHEMBL25101015 | 0.78 | TAAR1 (0.54) | AOC3SLC6A2SLC6A4SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861438-B2 | Antiviral agents | PFIZER (US) | 2005-03-01 | — | — | US | claimed |
| US-20040138449-A1 | Antiviral agents | PHARMACIA & UPJOHN COMPANY | 2004-07-15 | — | — | US | claimed |
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138449-A1 | Antiviral agents | IRF3, IFNAR1, EIF2AK2 | AOC3 4495/4885SLC6A2 2641/4885SLC6A4 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.