Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.60 |
| ▸ | UTS2R | Q9UKP6 | 10/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14775340 | 0.98 | AOC3 (0.58) | AOC3UTS2RGAAALDH1A1MAPT | |
| SCHEMBL11382002 | 0.91 | AOC3 (0.51) | AOC3UTS2RGAAALDH1A1 | |
| SCHEMBL19407138 | 0.83 | AOC3 (0.54) | AOC3UTS2RGAAALDH1A1MAPT | |
| SCHEMBL6479388 | 0.81 | AOC3 (0.74) | AOC3ALDH1A1MAPT | |
| SCHEMBL11434704 | 0.81 | LTA4H (0.54) | UTS2RALDH1A1 | |
| SCHEMBL19742702 | 0.80 | AOC3 (0.64) | AOC3UTS2R | |
| SCHEMBL4450372 | 0.79 | GAA (0.58) | AOC3GAAALDH1A1MAPT | |
| SCHEMBL9245675 | 0.79 | GAA (0.58) | AOC3GAAALDH1A1MAPT | |
| SCHEMBL5488204 | 0.79 | AOC3 (0.58) | AOC3GAAALDH1A1MAPT | |
| SCHEMBL5463519 | 0.79 | UTS2R (0.46) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043921-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-ARYL-3-HYDROXYMETHYL-1-METHYLPIPERIDINES. | NATCO PHARMA LIMITED (IN) | 2004-05-27 | — | — | WO | disclosed |
| EP-0399504-B1 | Aryloxyphenylpropylamines their preparation and use | NOVO NORDISK AS (DK) | 1995-05-03 | — | — | EP | disclosed |
| US-5310756-A | Aryloxyphenylpropylamines and their calcium overload blocking compositions and methods of use | NOVO NORDISK A/S (DK) | 1994-05-10 | — | — | US | disclosed |
| US-5145870-A | Treating calcium overload in brain cells, anoxia, migraine, ischemia, epilepsy, neurodegenerative diseases | NOVO NORDISK A/S (DK) | 1992-09-08 | — | — | US | disclosed |
| EP-0399504-A2 | Aryloxyphenylpropylamines their preparation and use | NOVO NORDISK A/S (DK) | 1990-11-28 | — | — | EP | disclosed |