Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 9/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479470 | 1.00 | FOLH1 (0.53) | FOLH1GSRRNPEPMMP2MMP9 | |
| SCHEMBL8734 | 0.94 | FOLH1 (0.46) | FOLH1GSRRNPEPMMP2MMP9 | |
| SCHEMBL8735 | 0.94 | FOLH1 (0.46) | FOLH1GSRRNPEPMMP2MMP9 | |
| SCHEMBL2873029 | 0.94 | FOLH1 (0.46) | FOLH1GSRRNPEPMMP2MMP9 | |
| Hydrochloric Acid SCHEMBL1560135 | 0.92 | FOLH1 (0.45) | FOLH1GSRRNPEPMMP2MMP9 | |
| Hydrochloric Acid SCHEMBL1560136 | 0.92 | FOLH1 (0.45) | FOLH1GSRRNPEPMMP2MMP9 | |
| Hydrochloric Acid SCHEMBL21933053 | 0.91 | FOLH1 (0.44) | FOLH1GSRRNPEPMMP2MMP9 | |
| Ornithine SCHEMBL3820639 | 0.86 | GSR (0.56) | FOLH1GSR | |
| SCHEMBL7198450 | 0.85 | FOLH1 (0.50) | FOLH1GSRRNPEPMMP2MMP9 | |
| SCHEMBL1443500 | 0.84 | FOLH1 (0.56) | FOLH1GSRRNPEPMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005067980-A2 | DESIGN OF THERAPEUTICS AND THERAPEUTICS | POINTILLISTE, INC. (US) | 2005-07-28 | — | — | WO | disclosed |
| EP-1542667-A2 | UREIDO SUBSTITUTED BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE | PTC Therapeutics, Inc. (US) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004009558-A2 | UREIDO SUBSTITUTED BENZOIC ACID COMPOUNDS, THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASES CAUSED BY SUCH MUTATIONS | PTC THERAPEUTICS, INC. (US) | 2004-01-29 | — | — | WO | disclosed |