SCHEMBL1443500

SCHEMBL1443500

NCCCC[C@H](NC(C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.56
GSR P00390 1/20 0.52
RNPEP Q9H4A4 1/20 0.50
CPB2 Q96IY4 10/20 0.46
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
SLC6A5 Q9Y345 1/20 0.43
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ACE P12821 1/20 0.39
CYP2D6 P10635 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1443498 1.00 FOLH1 (0.56) FOLH1GSRRNPEPCPB2MMP2
SCHEMBL8576386 0.98 FOLH1 (0.54) FOLH1GSRRNPEPCPB2MMP2
Water SCHEMBL1645999 0.98 FOLH1 (0.54) FOLH1GSRRNPEPCPB2MMP2
SCHEMBL7107134 0.98 FOLH1 (0.54) FOLH1GSRRNPEPCPB2MMP2
SCHEMBL38651131 0.85 FOLH1 (0.58) FOLH1GSRRNPEPCPB2MMP2
SCHEMBL8576380 0.85 FOLH1 (0.46) FOLH1GSRRNPEPCPB2MMP2
SCHEMBL3727817 0.84 FOLH1 (0.53) FOLH1GSRRNPEPCPB2MMP2
SCHEMBL6479470 0.84 FOLH1 (0.53) FOLH1GSRRNPEPCPB2MMP2
SCHEMBL209237 0.84 FOLH1 (0.53) FOLH1GSRRNPEPCPB2MMP2
SCHEMBL1413149 0.84 FOLH1 (0.53) FOLH1GSRRNPEPCPB2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290678-A Biological microsphere and preparation method and application thereof 康码(上海)生物科技有限公司 2024-07-05 CN claimed
CN-113512152-B Vinyl monomer-polyvinyl cross-linking agent copolymer non-porous microsphere and preparation method and application thereof 深圳普门科技股份有限公司 2022-05-10 CN claimed
CN-113512152-A Vinyl monomer-polyvinyl cross-linking agent copolymer non-porous microsphere and preparation method and application thereof 深圳普门科技股份有限公司 2021-10-19 CN claimed
US-10989681-B2 Grid coatings for capture of proteins and other compounds PURDUE RESEARCH FOUNDATION (US) 2021-04-27 US claimed
US-20210041388-A1 GRID COATINGS FOR CAPTURE OF PROTEINS AND OTHER COMPOUNDS PURDUE RESEARCH FOUNDATION 2021-02-11 US claimed
US-RE50618-E1 Anionic-core composition for delivery of therapeutic agents, and methods of making and using the same PHARMAIN CORPORATION (US) 2025-10-07 US disclosed
CN-118290678-A Biological microsphere and preparation method and application thereof 康码(上海)生物科技有限公司 2024-07-05 CN disclosed
CN-115850149-B Amino acid derivative with bitter suppressing effect and preparation method thereof 华南理工大学 2024-04-26 CN disclosed
US-11965851-B2 Grid coatings for capture of proteins and other compounds PURDUE RESEARCH FOUNDATION (US) 2024-04-23 US disclosed
US-20230183613-A1 USE OF CARBOXYMETHYLATED POLYMER OF LYSINES AS DISPERSING AGENT AND COMPOSITIONS COMPRISING THE SAME BASF SE (DE) 2023-06-15 US disclosed
CN-115850149-A Amino acid derivative with bitter taste inhibiting effect and preparation method thereof 华南理工大学 2023-03-28 CN disclosed
EP-4150039-A1 USE OF CARBOXYMETHYLATED POLYMER OF LYSINES AS DISPERSING AGENT AND COMPOSITIONS COMPRISING THE SAME BASF SE (DE) 2023-03-22 EP disclosed
WO-2011038356-A2 NOVEL LIVER-TARGETING AGENTS AND THEIR SYNTHESIS JOHNS HOPKINS UNIVERSITY (US) 2011-03-31 WO disclosed
WO-2011031771-A1 ANIONIC-CORE COMPOSITION FOR DELIVERY OF THERAPEUTIC AGENTS, AND METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2011-03-17 WO disclosed
WO-2011031284-A1 POLYMERIC CARRIER COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS, METHODS OF MAKING AND USING THE SAME PHARMAIN CORPORATION (US) 2011-03-17 WO disclosed
US-7087165-B2 Integrated high throughput system for the analysis of biomolecules INTRINSIC BIOPROBES, INC. (US) 2006-08-08 US disclosed
US-7087164-B2 Integrated high throughput system for the analysis of biomolecules INTRINSIC BIOPROBES, INC. (US) 2006-08-08 US disclosed
US-20040265843-A1 INTEGRATED HIGH THROUGHPUT SYSTEM FOR THE ANALYSIS OF BIOMOLECULES INTRINSIC BIOPROBES, INC. 2004-12-30 US disclosed
US-20040265844-A1 INTEGRATED HIGH THROUGHPUT SYSTEM FOR THE ANALYSIS OF BIOMOLECULES INTRINSIC BIOPROBES, INC. 2004-12-30 US disclosed
US-20030003223-A1 Methods and compositions for binding histidine-containing proteins to substrates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10989681-B2 Grid coatings for capture of proteins and other compounds CD2BP2, CDC37, DSTN FOLH1 1786/4885GSR 3088/4885RNPEP 1076/4885
US-20030003223-A1 Methods and compositions for binding histidine-containing proteins to substrates STUB1, SPR, CAD FOLH1 566/4885GSR 4316/4885RNPEP 318/4885
US-11965851-B2 Grid coatings for capture of proteins and other compounds CD2BP2, CDC37, CD68 FOLH1 1417/4885GSR 3193/4885RNPEP 975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.