Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
| ▸ | GABRE | P78334 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13229587 | 0.81 | CFTR (0.63) | NPC1RAB9ACYP3A4HTR3AGABRA1 | |
| SCHEMBL6205660 | 0.80 | ADORA2A (0.68) | POLBADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7479578 | 0.80 | ADORA2A (0.61) | POLBADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13229581 | 0.80 | CYP3A4 (0.55) | POLBRAB9ACYP3A4HTR3AKDM4E | |
| SCHEMBL2793777 | 0.76 | CYP3A4 (0.50) | SMN1; SMN2CYP3A4HTR3AKDM4EKMT2A | |
| SCHEMBL8251765 | 0.76 | GABRP (0.74) | POLBADORA2ANPC1RAB9AGABRP | |
| SCHEMBL13229634 | 0.75 | CYP3A4 (0.48) | POLBCYP3A4HTR3AKDM4E | |
| SCHEMBL13229624 | 0.74 | CFTR (0.48) | POLBNPC1SMN1; SMN2CYP3A4HTR3A | |
| SCHEMBL14944426 | 0.73 | ADORA2A (0.60) | ADORA2ANPC1RAB9ASMN1; SMN2ADORA1 | |
| SCHEMBL13229697 | 0.72 | CYP3A4 (0.49) | NPC1RAB9ASMN1; SMN2CYP3A4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861438-B2 | Antiviral agents | PFIZER (US) | 2005-03-01 | — | — | US | disclosed |
| US-20040138449-A1 | Antiviral agents | PHARMACIA & UPJOHN COMPANY | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138449-A1 | Antiviral agents | IRF3, IFNAR1, EIF2AK2 | POLB 254/4885ADORA2A 2551/4885NPC1 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.