Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037012 | 0.88 | ALDH1A1 (0.56) | FTOALDH1A1HPGDALOX12BRCA1 | |
| SCHEMBL7907421 | 0.87 | ALDH1A1 (0.53) | FTOALDH1A1HPGDALOX12BRCA1 | |
| SCHEMBL5496952 | 0.87 | FTO (0.55) | FTOALDH1A1HPGDALOX12BRCA1 | |
| SCHEMBL17515090 | 0.86 | ALDH1A1 (0.55) | FTOALDH1A1HPGDALOX12BRCA1 | |
| SCHEMBL20832 | 0.86 | ALDH1A1 (0.60) | FTOALDH1A1HPGDALOX12BRCA1 | |
| SCHEMBL25220939 | 0.86 | HPGD (0.52) | FTOALDH1A1HPGDALOX12BRCA1 | |
| SCHEMBL5766493 | 0.86 | ALDH1A1 (0.52) | FTOALDH1A1HPGDALOX12BRCA1 | |
| SCHEMBL9405138 | 0.86 | FTO (0.54) | FTOALDH1A1HPGDALOX12BRCA1 | |
| SCHEMBL139173 | 0.85 | FTO (0.65) | FTOALDH1A1HPGDALOX12BRCA1 | |
| SCHEMBL29044412 | 0.85 | ALDH1A1 (0.67) | FTOALDH1A1HPGDALOX12BRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007082-A2 | TREATMENT OF CHRONIC BACTERIAL INFECTION | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2005-01-27 | — | — | WO | disclosed |