SCHEMBL647958

SCHEMBL647958

COC(OC)C(=O)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13959147 0.76
SCHEMBL1126846 0.76 ALDH1A1 (0.44)
SCHEMBL2651657 0.74
SCHEMBL11117617 0.72
SCHEMBL3297298 0.70 MGAM (0.48)
SCHEMBL8838659 0.70 MGAM (0.48)
SCHEMBL8210537 0.70 LDHA (0.40)
SCHEMBL3236585 0.70 ALDH1A1 (0.42)
SCHEMBL10364910 0.69
SCHEMBL29781019 0.69 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109554396-B Imidazole derivative and gene delivery system thereof 复旦大学 2023-03-17 CN disclosed
CN-109554396-A A kind of imdazole derivatives and its gene pass release system 复旦大学 2019-04-02 CN disclosed
US-20190040073-A1 NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF SCIFLUOR LIFE SCIENCES, INC. 2019-02-07 US disclosed
US-10118929-B2 Nonanoic and decanoic acid derivatives and uses thereof SCIFLUOR LIFE SCIENCES, INC. (US) 2018-11-06 US disclosed
WO-2017189828-A1 NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF SCIFLUOR LIFE SCIENCES, INC. (US) 2017-11-02 WO disclosed
US-20170313708-A1 NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF FELIQS CORPORATION (JP) 2017-11-02 US disclosed
US-20170313708-A1 NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF FELIQS CORPORATION (JP) 2017-11-02 US disclosed
US-20170313708-A1 NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF FELIQS CORPORATION (JP) 2017-11-02 US disclosed
US-8304419-B2 Chemical compounds GLAXOSMITHKLINE LLC (US) 2012-11-06 US disclosed
US-8119665-B2 Aryl imidazoles and related compounds as C5a receptor modulators NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) 2012-02-21 US disclosed
US-20070149499-A1 Process for preparing beta-lactamase inhibitors WYETH (US) 2007-06-28 US disclosed
US-20070149499-A1 Process for preparing beta-lactamase inhibitors WYETH (US) 2007-06-28 US disclosed
US-20070149499-A1 Process for preparing beta-lactamase inhibitors WYETH (US) 2007-06-28 US disclosed
US-7186734-B2 Aryl imidazoles and related compounds as C5a receptor modulators NEUROGEN CORPORATION (US) 2007-03-06 US disclosed
US-7186734-B2 Aryl imidazoles and related compounds as C5a receptor modulators NEUROGEN CORPORATION (US) 2007-03-06 US disclosed
WO-2007024859-A2 PROCESS FOR PREPARING BETA-LACTAMASE INHIBITORS WYETH (US) 2007-03-01 WO disclosed
WO-2007024859-A2 PROCESS FOR PREPARING BETA-LACTAMASE INHIBITORS WYETH (US) 2007-03-01 WO disclosed
EP-1490343-A1 NEW ARYL IMIDAZOLES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS Neurogen Corporation (US) 2004-12-29 EP disclosed
US-20040116424-A1 Aryl imidazoles and related compounds as C5a receptor modulators NEUROGEN CORPORATION 2004-06-17 US disclosed
WO-2003082829-A1 NEW ARYL IMIDAZOLES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2003-10-09 WO disclosed