Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | PNPLA2 | Q96AD5 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953469 | 0.85 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1PNPLA2HDAC6MAPT | |
| SCHEMBL13874177 | 0.78 | APP (0.41) | L3MBTL1ALDH1A1MAPTNPC1 | |
| SCHEMBL2947361 | 0.75 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1HDAC6MAPTNPC1 | |
| SCHEMBL2953418 | 0.75 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MAPTNPC1 | |
| SCHEMBL10133348 | 0.74 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1MAPT | |
| SCHEMBL2953052 | 0.74 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1HDAC6CDK1CDK5 | |
| SCHEMBL13240036 | 0.73 | L3MBTL1 (0.68) | L3MBTL1ALDH1A1MAPTNPC1 | |
| SCHEMBL13240038 | 0.73 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1MAPTNPC1 | |
| SCHEMBL10310318 | 0.72 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1MAPTNPC1 | |
| SCHEMBL2953422 | 0.72 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846919-B2 | Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof | ARENA PHARMACEUTICALS, INC. (US) | 2005-01-25 | — | — | US | disclosed |